tio2 chemical supplier

The manufacturing process of titanium dioxide typically involves mining ilmenite, rutile, or anatase from natural sources, followed by conversion into TiO2 through various chemical processes. The resulting TiO2 can then be further processed to achieve different particle sizes and coatings that optimize its performance in specific applications. For instance, TiO2 used in sunscreens is often coated to enhance its effectiveness in blocking UV rays without causing skin irritation.

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For research published in 2022 study in the journal Food and Chemical Toxicology, scientists examined “the genotoxicity and the intracellular reactive oxygen species induction by physiologically relevant concentrations of three different TiO2 nanomaterials in Caco-2 and HT29-MTX-E12 intestinal cells, while considering the potential influence of the digestion process in the NMs’ physiochemical characteristics.” They found a “DNA-damaging effect dependent on the nanomaterial,” along with the micronucleus assay suggesting “effects on chromosomal integrity, an indicator of cancer risk, in the HT29-MTX-E12 cells, for all the tested TiO2 nanomaterials.” Researchers concluded that the results showcase “evidence of concern” regarding titanium dioxide used as a food additive.

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